Thermo Fisher Scientific APLP1 Monoclonal Antibody (354008)
인간 APLP1 단백질을 인식하는 Mouse IgG2b 단클론 항체로, ICC/IF에 적합합니다. Lyophilized 형태이며 PBS + trehalose 버퍼에 보존됩니다. 높은 특이성과 교차반응성 검증 완료. 연구용으로만 사용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 8–25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 354008 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human APLP-1 (Gln34–Glu580, predicted) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608601 |
Product Specific Information
- In direct ELISAs and Western blots, 100% cross-reactivity with recombinant mouse APLP-1 is observed.
- No cross-reactivity with recombinant human APLP-2 is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
This gene encodes a member of the highly conserved amyloid precursor protein gene family.
The encoded protein is a membrane-associated glycoprotein cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage.
This cleavage releases an intracellular fragment that may act as a transcriptional activator.
The protein may also play a role in synaptic maturation during cortical development.
Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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