Thermo Fisher Scientific CD142 Monoclonal Antibody (355220)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Product Specifications

Host/Isotype

Rat / IgG2c

Class

Monoclonal

Type

Antibody

Clone

355220

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Coagulation Factor III Ala29-Glu251 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD142,uniProtId:P20352-1,ncbiNodeId:10090,antigenRange:29-251,antigenLength:294,antigenImageFileName:MA5-24102_CD142_P20352-1_Rat.svg,antigenImageFileNamePDP:MA5-24102_CD142_P20352-1_Rat_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2609243

Product Specific Information

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.