Thermo Fisher Scientific BMPR1B Monoclonal Antibody (2E2)
BMPR1B 단백질을 인식하는 Mouse monoclonal antibody (Clone 2E2). Western blot과 ELISA에 적합하며, Human 및 Mouse 시료에 반응. PBS buffer에 보관되며, 동결·해동 반복은 피해야 함. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2E2 |
| Immunogen | BMPR1B (AAH47773.1, 24 a.a.–127 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
TPRPKVLRCK CHHHCPEDSV NNICSTDGYC FTMIEEDDSG LPVVTSGCLG LEGSDFQCRD TPIPHQRRSI ECCTERNECN KDLHPTLPPL KNRDFVDGPI HHRA
Target Information
BMPR1B (also known as ALK6, CDw293) is a member of the transmembrane serine/threonine kinase family, part of the bone morphogenetic protein (BMP) receptor group closely related to activin receptors ACVR1 and ACVR2.
BMPR1B is mainly involved in endochondral bone formation and embryogenesis. It is expressed in normal and cancerous prostate tissues and is relevant in endocrine therapy for prostate cancer patients. BMPR1B receptor trafficking also plays a significant role in FOP pathogenesis and human T-cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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