Thermo Fisher Scientific MKL1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MKL1. Validated for IHC (paraffin) with 1:50–1:200 dilution. Affinity-purified with >95% purity. Supplied as liquid, 1 mg/mL, unconjugated. Store at 4°C short term or -20°C long term.
- 카탈로그번호
- PA575295
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminal of Human MKL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719023 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen.
Purity is greater than 95% as determined by SDS-PAGE.
Target Information
The protein encoded by the MKL1 gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation.
It is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus.
A specific translocation event involving this gene and the RNA-binding motif protein-15 gene has been associated with acute megakaryocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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