Thermo Fisher Scientific TPT1 Polyclonal Antibody
TPT1 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. WB, IHC, ICC/IF 등 다양한 응용에 적합하며, 높은 순도(>95%)로 정제됨. Human, Mouse, Rat 반응성. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 70–120 of Human HRF |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803159 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium-binding proteins. It is localized in the cytoplasm and widely expressed, functioning as a transcriptional activator, calcium transporter, histamine inducer, and antiapoptotic caspase 3 inhibitor.
TPT1 acts as a cytokine-like molecule that triggers the release of histamine, IL-4, and IL-13 from basophils, as well as IL-8 secretion and calcium response in eosinophils.
It plays a pivotal role in allergic diseases and is implicated in neurodegenerative disorders such as Alzheimer’s disease and Down syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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