Thermo Fisher Scientific MRPL10 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:1,000

Product Specifications

Product Specific Information

• Recommended positive control: 293T
• Predicted reactivity: Human (99%), Mouse (83%), Rat (86%), Rhesus Monkey (97%), Bovine (90%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and assist in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, unlike prokaryotic ribosomes where this ratio is reversed. Mammalian mitoribosomes lack a 5S rRNA. The proteins that make up the mitoribosome vary greatly among species, complicating identification by sequence homology. The MRPL10 gene encodes a 39S subunit protein, and a pseudogene corresponding to this gene is found on chromosome 5q.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.