Thermo Fisher Scientific ACTA1 Polyclonal Antibody
ACTA1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간·마우스·랫에서 반응합니다. WB, IHC, ICC/IF, IP 등 다양한 응용에 사용 가능하며, 고순도 액상 형태로 제공됩니다. 세포 구조 및 근육 관련 연구에 적합합니다.
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Thermo Fisher Scientific ACTA1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ACTA1 (Accession P68133), corresponding to amino acid residues M1–P34 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818389 |
Product Specific Information
This antibody detects endogenous levels of total Actin alpha 1.
Target Information
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved and play crucial roles in cell motility, structure, and integrity. Alpha, beta, and gamma actin isoforms have been identified:
- Alpha actins: Major constituents of the contractile apparatus.
- Beta and gamma actins: Involved in cell motility regulation.
This actin is an alpha actin found in skeletal muscle. Mutations in this gene are associated with:
- Nemaline myopathy type 3
- Congenital myopathy with excess thin myofilaments
- Congenital myopathy with cores
- Congenital myopathy with fiber-type disproportion
These conditions lead to muscle fiber defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-99456_ACTA1_P68133-1_Rabbit.svg, PA5-99456_ACTA1_P68133-1_Rabbit_PDP.jpeg)
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