Thermo Fisher Scientific COL6A2 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200

Product Specifications

Product Specific Information

Immunogen sequence:
ELSFVFLTDGV TGNDSLHESA HSMRKQNVVP TVLALGSDVD MDVLTTLSLG DRAAVFHEKD YDSLAQPGFF DRFIR

• Highest antigen sequence identity to orthologs: mouse 86%, rat 86%

Target Information

This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues.
The product of this gene contains several domains similar to von Willebrand Factor type A domains.
These domains have been shown to bind extracellular matrix proteins, explaining the importance of this collagen in organizing matrix components.
Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy.
Three transcript variants have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.