Thermo Fisher Scientific SPG20 Polyclonal Antibody
Human SPG20 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 0.7 mg/mL 농도의 액상 형태입니다. SPG20 단백질의 세포내 수송 및 미토콘드리아 기능 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human SPG20. Recombinant protein control fragment (Product #RP-105956) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.70 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664013 |
Product Specific Information
Immunogen sequence:
KEEAKNYYKQG IGHLLRGISI SSKESEHTGP GWESARQMQQ KMKETLQNVR TRLEILEKGL ATSLQNDLQE VPKLYPEFPP KDMCEKLPEP QSFSSAPQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 81%
Target Information
SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondrial function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of the EGF receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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