Thermo Fisher Scientific ABCC11 Monoclonal Antibody (MRP8 7C12/4)
ABCC11 단백질을 표적하는 mouse IgM 단클론 항체로, Western blot, Flow cytometry, ELISA 등 다양한 어세이에 사용 가능. 인간 MRP8 재조합 단백질로 면역화된 항체이며, 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
Flow Cytometry (Flow)
ELISA
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MRP8 7C12/4 |
| Immunogen | Recombinant Human MRP8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1958406 |
Product Specific Information
Western blot detects a band of approximately 82 kDa.
A suggested positive control for this product is neutrophil lysate (particularly neutrophils from spleen).
Target Information
ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters.
ABC proteins transport various molecules across extra- and intra-cellular membranes.
ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This ABC full transporter belongs to the MRP subfamily, which is involved in multi-drug resistance.
The gene product participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides.
A SNP in this gene determines human earwax type.
ABCC11 and its family member ABCC12 are derived by duplication and both localized to chromosome 16q12.1.
Multiple alternatively spliced transcript variants have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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