Thermo Fisher Scientific CD200 Monoclonal Antibody (MRC OX90)
마우스 CD200 단백질을 검출하는 Rat IgG2a 단일클론 항체로, IHC, Flow Cytometry, ELISA 등에 사용 가능. 단백질 G 정제, PBS 버퍼 및 0.02% sodium azide 포함. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 보관 권장.
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MRC OX90 |
| Immunogen | Mouse CD200-rat CD4 fusion protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2073828 |
Product Specific Information
MA1-90713 detects CD200 from mouse samples.
Target Information
CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains and belongs to the immunoglobulin superfamily. It is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies in mouse and rat suggest that CD200 may regulate myeloid cell activity and deliver an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants encoding different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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