Thermo Fisher Scientific SN38 Recombinant Rabbit Monoclonal Antibody (PSH0-05)
SN38에 특이적인 재조합 토끼 단클론 항체로 Western blot 및 ELISA에 적합합니다. HEK293 세포에서 발현되었으며 Protein A로 정제되었습니다. 1 mg/mL 농도의 액상 형태로 제공되며, 4°C 단기 보관 또는 -20°C 장기 보관이 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PSH0-05 |
| Immunogen | SN38-OVA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3090453 |
Product Specific Information
Product MA5-50767 was used in a Competitive ELISA and Indirect ELISA.
Target Information
SN38 is a chemical compound that belongs to the class of topoisomerase I inhibitors. It is the active metabolite of irinotecan, a chemotherapeutic drug used in the treatment of various types of cancer, particularly colorectal cancer. SN38 exerts its anti-cancer effects by inhibiting the action of topoisomerase I, an enzyme involved in DNA replication and repair. By inhibiting this enzyme, SN38 prevents DNA from unwinding, leading to the accumulation of DNA damage and ultimately inducing cell death in cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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