Thermo Fisher Scientific SN38 Recombinant Rabbit Monoclonal Antibody (PSH0-06)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Chemical

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

PSH0-06

Immunogen

SN38-OVA

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 0.1% BSA, 40% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3090454

Product Specific Information

Product MA5-50768 was used in a Competitive ELISA and Indirect ELISA.

Target Information

SN38 is a chemical compound that belongs to the class of topoisomerase I inhibitors. It is the active metabolite of irinotecan, a chemotherapeutic drug used in the treatment of various types of cancer, particularly colorectal cancer. SN38 exerts its anti-cancer effects by inhibiting the action of topoisomerase I, an enzyme involved in DNA replication and repair. By inhibiting this enzyme, SN38 prevents DNA from unwinding, leading to the accumulation of DNA damage and ultimately inducing cell death in cancer cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.