Thermo Fisher Scientific DOCK8 Monoclonal Antibody (OTI4H10), TrueMAB
DOCK8 단백질을 인식하는 마우스 단클론 항체로 Western blot 및 IHC(P) 실험에 적합. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제, 보존제 무첨가. 연구용으로 면역반응 및 B세포 시냅스 연구에 활용 가능.
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Thermo Fisher Scientific DOCK8 Monoclonal Antibody (OTI4H10), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 832–1160 of human DOCK8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The Dedicator of cytokinesis protein 8 (DOCK8) belongs to the DOCK180 family of guanine nucleotide exchange factors.
DOCK8 is essential for humoral immune responses and proper formation of the B cell immunological synapse.
Mutations in this gene cause the autosomal recessive form of hyper-IgE syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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