Thermo Fisher Scientific DVL2 Monoclonal Antibody (OTI1B12), TrueMAB
Human DVL2 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western blot에 적합합니다. TrueMAB 형식의 고순도 항체이며, PBS 버퍼에 동결건조 상태로 제공됩니다. 연구용으로만 사용 가능하며 Wnt 신호전달 관련 연구에 유용합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–320 of human DVL2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Disheveled DVL2 is a member of the dishevelled (dsh) protein family. Vertebrate dsh proteins share approximately 40% amino acid sequence similarity with Drosophila dsh.
This gene encodes a 90 kDa protein that undergoes posttranslational phosphorylation to form a 95 kDa cytoplasmic protein, which may play a role in Wnt-mediated signal transduction. The mechanisms of dishevelled function in Wnt signaling are likely conserved among metazoans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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