Thermo Fisher Scientific ULBP2 Recombinant Rabbit Monoclonal Antibody (003)
Human ULBP2 단백질을 인식하는 재조합 토끼 단클론 항체로, 높은 특이성과 민감도를 제공합니다. ELISA에 적합하며, 로트 간 일관성과 방부제 없는 포뮬레이션으로 안정적입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 003 |
| Immunogen | Recombinant Human ULBP2 protein (Met1–Ser217) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785696 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Specific antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to large rabbit immune repertoire
This antibody shows specificity for Human ULBP2.
Target Information
ULBP2 encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells. This interaction triggers cytokine and chemokine release, promoting NK cell recruitment and activation. The mature protein may be membrane-anchored via a glycosylphosphatidylinositol moiety or secreted.
Many malignant cells secrete ULBP2 to evade NK cell-mediated immunosurveillance. The ULBP2 gene is located within a cluster of MHC class I-related genes on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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