Thermo Fisher Scientific Adenylate Cyclase 5/6 Polyclonal Antibody
Rabbit polyclonal antibody for Adenylate Cyclase 5/6 detection in human, mouse, and rat samples. Validated for WB, IHC, and ICC/IF. Affinity-purified with >95% purity. Supplied as liquid, unconjugated, for research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1111–1160 of Human ADCY5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719002 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. Purity is >95% as determined by SDS-PAGE.
Target Information
Adenylate cyclase 5/6 encodes a member of the membrane-bound adenylyl cyclase enzymes. These enzymes mediate G protein-coupled receptor signaling through synthesis of the second messenger cAMP. The encoded protein’s activity is stimulated by the Gs alpha subunit and inhibited by protein kinase A, calcium, and Gi alpha subunits. Polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternative splicing results in multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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