Thermo Fisher Scientific Phospho-AKT Pan (Thr450, Thr451, Thr447) Recombinant Rabbit Monoclonal Antibody (8U6D2)
Phospho-AKT Pan (Thr450, Thr451, Thr447) 항체는 인간, 마우스, 랫트 반응성을 가지며, 세포 생존 및 성장 조절 연구에 적합한 recombinant rabbit monoclonal antibody입니다. Western blot, IHC, ELISA에 사용 가능하며 고순도, 안정적 액상 형태로 제공됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8U6D2 |
| Immunogen | A synthetic phosphorylated peptide around T450 of human Akt |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.85 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094418 |
Product Specific Information
Immunogen sequence: TITPP
Target Information
AKT, also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival, and growth by phosphorylating multiple proteins. This kinase is activated by insulin, PI3K, IGF1, and various growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of targets including forkhead transcription factors and caspase-9. The AKT pathway is a major target for cancer drug discovery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- MA5-51537_AKT_Pan_P31749-1_Rabbit.svg
- MA5-51537_AKT_Pan_P31749-1_Rabbit_PDP.jpeg
- MA5-51537_AKT_Pan_P31751-1_Rabbit.svg
- MA5-51537_AKT_Pan_P31751-1_Rabbit_PDP.jpeg
- MA5-51537_AKT_Pan_Q9Y243-1_Rabbit.svg
- MA5-51537_AKT_Pan_Q9Y243-1_Rabbit_PDP.jpeg
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