Thermo Fisher Scientific TrkC Polyclonal Antibody
Rabbit polyclonal antibody recognizing TrkC protein in mouse and rat. Suitable for WB and IHC applications. Lyophilized form with whole serum, no preservative. Store at 4°C short-term or -20°C long-term. For research use only.
- 카탈로그번호
- OST00334W-100UL
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous PubMed (Misc) | – | View 2 publications |
Product Specifications
| Category | Details |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of mouse TrkC conjugated to blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TrkC.
Target Information
NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system.
Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1.
The different isoforms do not have identical signaling properties.
The protein is widely expressed, mainly in the nervous tissue.
Isoform B is expressed in a relatively large amount in the adult brain compared to the fetal brain.
TRKC is subject to ligand-mediated auto-phosphorylation.
The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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