Thermo Fisher Scientific Epstein Barr Virus Nuclear Antigen 1 Polyclonal Antibody

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Virus

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant EBNA-1.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

5 mg/mL

Purification

IgG fraction

Storage buffer

PBS, pH 7.2

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1017063

Product Specific Information

The PA1-7497 antibody detects Epstein-Barr nuclear antigen (EBNA-1).

PA1-7497 has been successfully used in ELISA and Western blot applications. Potential applications for PA1-7497 include fluorescence microscopy and immunohistochemistry.

The PA1-7497 antibody was raised against recombinant EBNA-1.

Target Information

Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkins disease and Burkitts Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.