Thermo Fisher Scientific AP3B1 Polyclonal Antibody
Thermo Fisher Scientific의 AP3B1 폴리클로날 항체로, Human, Mouse, Rat에서 반응합니다. WB, IHC, ELISA에 사용 가능하며 고순도 Affinity Chromatography로 정제되었습니다. 세포 내 소기관 연구 및 단백질 위치 분석에 적합합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 895–1094 of human AP3B1 (NP_003655.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.68 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2914627 |
Product Specific Information
Positive test controls include SKOV3, SW620, and Mouse liver.
The target is usually found in the following locations:
- Cytoplasmic side
- Cytoplasmic vesicle
- Golgi apparatus
- Peripheral membrane protein
- Clathrin-coated vesicle membrane
Immunogen sequence:
FGDKMVSIQI TLNNTTDRKI ENIHIGEKKL PIGMKMHVFN PIDSLEPEGS ITVSMGIDFC DSTQTASFQL CTKDDCFNVN IQPPVGELLL PVAMSEKDFK KEQGVLTGMN ETSAVIIAAP QNFTPSVIFQ KVVNVANVGA VPSGQDNIHR FAAKTVHSGS LMLVTVELKE GSTAQLIINT EKTVIGSVLL RELKPVLSQG
Target Information
AP3B1 is a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Structurally, AP3B1 is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in AP3B1 are associated with Hermansky-Pudlak syndrome type 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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