
Thermo Fisher Scientific HIRIP3 Polyclonal Antibody
HIRIP3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA에 적합합니다. 인간, 마우스, 랫트 반응성 보유. 고순도 친화 크로마토그래피 정제, -20°C 보관, 연구용 전용 시약.
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Thermo Fisher Scientific HIRIP3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 417–556 of human HIRIP3 (NP_003600.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.47 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914626 |
Product Specific Information
Positive test controls include: HL-60, HeLa, U-937, Jurkat, Mouse skeletal muscle, Mouse liver, Rat skeletal muscle.
The target is usually found in the following locations: Nucleus.
Immunogen sequence:
GRRGEDHPAV MRLKRYIRAC GAHRNYKKLL GSCCSHKERL SILRAELEAL GMKGTPSLGK CRALKEQREE AAEVASLDVA NIISGSGRPR RRTAWNPLGE AAPPGELYRR TLDSDEERPR PAPPDWSHMR GIISSDGESN
Target Information
The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in Saccharomyces cerevisiae.
The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex.
Several cDNAs encoding HIRA-interacting proteins (HIRIPs) have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in chromatin and histone metabolism.
Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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