Thermo Fisher Scientific alpha-Defensin 1 Polyclonal Antibody
Human 및 Mouse 시료에 반응하는 Rabbit Polyclonal Antibody로, DEFA1 유래 합성 펩타이드(aa 40–90)를 면역원으로 사용. Western blot 및 IHC(Paraffin) 적용 가능. 고순도 Affinity Chromatography 정제, 1 mg/mL 농도, PBS/glycerol buffer에 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: [References not provided]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DEFA1; DEFA1B (Accession P59665), corresponding to amino acid residues I40–W90 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852492 |
Product Specific Information
Antibody detects endogenous levels of total Defensin alpha1.
Target Information
Defensins are a family of microbicidal and cytotoxic peptides involved in host defense. They are abundant in neutrophil granules and also found in the epithelia of mucosal surfaces such as the intestine, respiratory tract, urinary tract, and vagina. Members share high sequence similarity and a conserved cysteine motif. The protein encoded by this gene, defensin alpha 1, is located in neutrophil granules and contributes to phagocyte-mediated defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin alpha 3 by only one amino acid and both exhibit copy number variation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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