Thermo Fisher Scientific Desmoplakin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 2609-2830 of human Desmoplakin (NP_0044062) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Desmoplakin,uniProtId:P15924-1,ncbiNodeId:9606,antigenRange:2609-2830,antigenLength:2871,antigenImageFileName:PA5-89145_Desmoplakin_P15924-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89145_Desmoplakin_P15924-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.42 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805386

Product Specific Information

Positive Samples: HepG2; Cellular Location: Cell junction, Cytoplasm, cytoskeleton, desmosome

Immunogen sequence: FSDTLEESSP IAAIFDTENL EKISITEGIE RGIVDSITGQ RLLEAQACTG GIIHPTTGQK LSLQDAVSQG VIDQDMATRL KPAQKAFIGF EGVKGKKKMS AAEAVKEKWL PYEAGQRFLE FQYLTGGLVD PEVHGRISTE EAIRKGFIDG RAAQRLQDTS SYAKILTCPK TKLKISYKDA INRSMVEDIT GLRLLEAASV SSKGLPSPYN MSSAPGSRSG SR

Target Information

Desmoplakin (DSP) is a major high molecular weight protein of the desmosomes. It is involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. Desmoplakin mutations are associated with Keratoderma and cardiomyopathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.