Thermo Fisher Scientific ACKR2, Atypical Chemokine Receptor 2 Polyclonal Antibody
Human ACKR2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB와 ICC/IF에 사용 가능. 합성 펩타이드 면역원으로 제작되었으며, 항원 친화 크로마토그래피로 정제됨. 액상 형태, 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관.
- 카탈로그번호
- 7TM0314N
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide representing the carboxyl-terminal tail of human ACKR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
This gene encodes a beta chemokine receptor predicted to be a seven-transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for recruiting effector immune cells to inflammation sites. This gene is expressed in various tissues and hemopoietic cells. Its expression in lymphatic endothelial cells and overexpression in vascular tumors suggest roles in leukocyte recirculation and vascular tumor development. It binds most beta-chemokine family members, though its specific function remains unclear. The gene is mapped to chromosome 3p21.3, within a cluster of chemokine receptor genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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