Thermo Fisher Scientific UBTF Monoclonal Antibody (6C6)
UBTF 단백질을 표적으로 하는 Thermo Fisher의 Mouse Monoclonal Antibody (Clone 6C6). Western blot, ICC/IF, ELISA에 최적화. Human 및 Rat 반응성. PBS 기반 액상 형태로 보존제 없음. -20°C 보관, 동결/해동 반복 피할 것.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6C6 |
| Immunogen | UBTF (NP_055048, 551 a.a. ~650 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
PPAATNSSKK MKFQGEPKKP PMNGYQKFSQ ELLSNGELNH LPLKERMVEI GSRWQRISQS QKEHYKKLAE EQQKQYKVHL DLWVKSLSPQ DRAAYKEYIS
Target Information
UBF-1 encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. It may also be involved in chromatin remodeling and pre-rRNA processing, regulated by phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed. Pseudogenes of this gene are located on chromosomes 3, 11 (short arm), and X, as well as the long arm of chromosome 11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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