Thermo Fisher Scientific Lambda Light Chain Recombinant Rabbit Monoclonal Antibody (ARC2357)
Thermo Fisher의 재조합 토끼 단클론 항체로 인간, 마우스, 랫트의 Lambda Light Chain 검출에 적합. WB, IHC(P), ELISA에 사용 가능하며 고순도 친화 크로마토그래피 정제. 안정한 액상 형태로 -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:6,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2357 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–117 of human Lambda Light Chain (P01701) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.37 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897945 |
Product Specific Information
- Positive Samples: Mouse spleen, Rat spleen
- Immunogen sequence:
MTCSPLLLTL LIHCTGSWAQ SVLTQPPSVS AAPGQKVTIS CSGSSSNIGN NYVSWYQQLP GTAPKLLIYD NNKRPSGIPD RFSGSKSGTS ATLGITGLQT GDEADYYCGT WDSSLSA
Target Information
Immunoglobulin classes share a basic four polypeptide chain structure composed of two heavy chains (five types) and two light chains (kappa, lambda; both ~22.5 kDa).
Kappa and lambda light chains each contain a variable and constant region, distinguishable by their antigenic properties.
The kappa to lambda ratio is typically 70:30.
Antibodies to the kappa light chain are useful for identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
Demonstration of clonality in lymphoid infiltrates indicates malignancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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