Thermo Fisher Scientific ZIC1-3 Polyclonal Antibody
ZIC1-3 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC에 사용 가능. 인간, 마우스, 랫트 반응성. Lyophilized 형태로 제공되며 PBS 버퍼에 보존. 연구용으로만 사용 가능.
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- OSZ00004G-500UG
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- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 5 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal region of human ZIC3 (Zinc finger protein ZIC3) conjugated to an immunogenic carrier protein. Target family: ZIC1/ZIC2/ZIC3, UniProt ID: O60481-1, Antigen range: 467. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in many species including rat and mouse.
- Specificity: ZIC1, ZIC2, ZIC3.
Target Information
Zic1 encodes a zinc finger protein expressed in the developing or matured central nervous system in a highly restricted manner. Zic is expressed in granule cells that make synaptic contact with Purkinje cells. Zic1 is critical to cerebellar pattern formation. Expression of Zic genes begins at gastrulation and neurulation, becoming restricted to dorsal neural ectoderm and dorsal paraxial mesoderm.
The Zic1 gene maps to chromosome 9 in mouse, with a region-specific enhancer essential for expression. Zic2 and Zic3 are highly similar; Zic2 is essential for brain formation, and Zic3 is important for right-left axis formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: OSZ00004G-500UG_ZIC1ZIC2ZIC3_O60481-1_Rabbit.svg, OSZ00004G-500UG_ZIC1ZIC2ZIC3_O60481-1_Rabbit_PDP.jpeg)
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