Thermo Fisher Scientific ZIC1-3 Polyclonal Antibody
ZIC1-3 단백질을 인식하는 Thermo Fisher Scientific의 goat polyclonal 항체로, WB 및 IHC에 사용 가능. 인간, 생쥐, 랫트 반응성. 동결건조 형태로 보존, 장기 보관 시 -20°C 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Goat / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal region of human ZIC3 conjugated to an immunogenic carrier protein. Target family: ZIC1/ZIC2/ZIC3; UniProt ID: O60481-1; NCBI Node ID: 9606; Antigen Range: 467; Antigen Length: 467 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in many species including rat and mouse.
- Specificity: ZIC1, ZIC2, ZIC3.
Target Information
Zic1 encodes a zinc finger protein expressed in the developing or matured central nervous system in a highly restricted manner. Zic is expressed in granule cells that make synaptic contact with Purkinje cells. Zic1 is critical to cerebellar pattern formation. Expression of Zic genes begins at gastrulation and neurulation, becoming restricted to dorsal neural ectoderm and paraxial mesoderm. The Zic1 gene maps to chromosome 9 in mouse. Its 5′ flanking region contains a region-specific enhancer essential for in-vivo and in-vitro function. Zic gene products show distinct temporal mRNA expression profiles. The Drosophila odd-paired gene is highly homologous to the Zic family. Zic2 and Zic3 are similar genes; Zic2 is essential for brain formation, and Zic3 is important for right-left axis formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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