Thermo Fisher Scientific ZIC1-3 Polyclonal Antibody
ZIC1-3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 적합. 인간, 마우스, 랫트 시료에 반응하며, 동결건조 형태로 제공. 장기 보관 시 -20°C에서 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from the C-terminal region of human ZIC3 (Zinc finger protein ZIC3) conjugated to blue carrier protein. The peptide is homologous in many species including rat and mouse. Specificity: ZIC1, ZIC2, ZIC3. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage buffer | Whole serum |
| Contains | No preservative |
| Storage conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide sequence is conserved among several species, including rat and mouse.
- Specificity: ZIC1, ZIC2, ZIC3.
Target Information
Zic1 encodes a zinc finger protein expressed in the developing or mature central nervous system in a highly restricted manner.
Zic is expressed in granule cells that make synaptic contact with Purkinje cells and is critical for cerebellar pattern formation.
Expression of Zic genes begins at gastrulation and neurulation, becoming restricted to dorsal neural ectoderm and dorsal paraxial mesoderm.
The Zic1 gene is mapped to chromosome 9 in mouse. The 5′ flanking region contains a region-specific enhancer essential for gene regulation.
Zic2 and Zic3 are highly homologous genes; Zic2 is essential for brain formation, while Zic3 is important for right-left axis formation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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