Thermo Fisher Scientific TGFBR3 Polyclonal Antibody
TGFBR3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 사용 가능. 인간 및 생쥐 반응성. 고순도 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
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- PA517529
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- pk
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Thermo Fisher Scientific TGFBR3 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in the extracellular domain of the type III TGF-ß receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 120.8 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11001447 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other family members under physiological conditions.
Target Information
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members.
Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling.
Decreased expression of this receptor has been observed in various cancers.
Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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