Thermo Fisher Scientific ATP1B1 Polyclonal Antibody
ATP1B1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제. PBS/glycerol buffer에 보존, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ATP1B1 (Accession P05026), corresponding to amino acid residues T67–Q117 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852221 |
Product Specific Information
This antibody detects endogenous levels of total ATP1B1.
Target Information
The ATP1B1 gene encodes a beta 1 subunit of the Na⁺/K⁺-ATPase, an integral membrane protein essential for maintaining electrochemical gradients of sodium and potassium ions across the plasma membrane. These gradients are critical for osmoregulation, sodium-coupled transport of various molecules, and electrical excitability of nerve and muscle cells. The enzyme consists of a large catalytic alpha subunit and a smaller glycoprotein beta subunit, which regulates the number of sodium pumps at the plasma membrane through alpha/beta heterodimer assembly. Multiple genes encode the glycoprotein subunit, and alternatively spliced transcript variants exist, though their biological significance is uncertain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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