Thermo Fisher Scientific Phospho-Chimaerin beta 2 (Ser171) Polyclonal Antibody, FITC
Phospho-Chimaerin beta 2 (Ser171) 인산화 특이적 폴리클로날 항체로, FITC 형광 표지 적용. Western blot, ELISA, IP 등 다양한 응용 가능. 사람, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 연구용 전용 제품.
- 카탈로그번호
- PCHIM-FITC
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Phospho-Chimaerin beta 2 (Ser171) Polyclonal Antibody, FITC
Applications 및 희석 배수
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Phosphorylated synthetic peptide corresponding to unique amino acid sequence on beta 2 Chimaerin protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain, and an SH2 domain.
The protein has GTPase-activating activity regulated by phospholipid binding, and diacylglycerol (DAG) induces translocation from the cytosol to the Golgi apparatus membrane.
It plays a role in proliferation and migration of smooth muscle cells.
Decreased expression is associated with high-grade gliomas and breast tumors, while increased expression is linked to lymphomas.
Mutations have been associated with schizophrenia in men.
Alternate transcriptional splice variants encoding different isoforms have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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