Thermo Fisher Scientific TMC6 Polyclonal Antibody
TMC6 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot, IHC, ICC/IF에 적합하며, 인체 및 마우스 시료 반응성. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공.
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Thermo Fisher Scientific TMC6 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide from near the center of human EVER1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage store at −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153950 |
Product Specific Information
- A suggested positive control is human spleen tissue lysate.
- PA5-20505 can be used with blocking peptide PEP-0625.
Target Information
TMC6 interacts with and forms a complex with the zinc transporter SLC30A1, localizing to the endoplasmic reticulum, nuclear membrane, and Golgi apparatus. Inactivation of the TMC6 gene is implicated in epidermodysplasia verruciformis (EV), an autosomal recessive dermatosis associated with abnormal susceptibility to human papillomaviruses (HPVs) and progression to squamous cell carcinoma on sun-exposed skin.
TMC6 encodes integral membrane proteins predicted to form transmembrane channels, featuring 10 transmembrane domains and 2 leucine zipper motifs.
Diseases associated with TMC6 include Epidermodysplasia Verruciformis and Superficial Mycosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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