Thermo Fisher Scientific PDE2A Polyclonal Antibody
Rabbit polyclonal antibody recognizing PDE2A in human, mouse, and rat. Validated for Western blot at 1:1,000–1:3,000 dilution. Detects endogenous PDE2A protein. Supplied as liquid, 1 mg/mL, in PBS with 50% glycerol. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PDE2A (Accession O00408), corresponding to amino acid residues L825–Q875 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2903408 |
Product Specific Information
Antibody detects endogenous levels of total PDE2A.
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kDa cyclic nucleotide phosphodiesterase (PDE). Three isoforms (PDE2A1, PDE2A2, PDE2A3) are produced by alternative splicing of a single gene. PDE2A degrades both cAMP and cGMP, with higher efficiency for cGMP. It is expressed in multiple tissues, most abundantly in the brain (cerebellum and neocortex). PDE2A is associated with regulation of endothelial barrier function and has been implicated in erectile dysfunction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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