Thermo Fisher Scientific SAP102 Polyclonal Antibody
DLG3 유래 합성 펩타이드를 면역원으로 한 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에서 SAP102 단백질 검출에 사용. Western blot에 적합하며, Affinity chromatography로 정제된 액상 형태. -20°C 보관.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SAP102 Polyclonal Antibody
Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DLG3 (Accession Q92796), corresponding to amino acid residues D638–D688. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903409 |
Product Specific Information
This antibody detects endogenous levels of total DLG3.
Target Information
Synapse-Associated Protein 102 (SAP102) is a plasma membrane-associated protein found in synaptic junctions. It contains three PDZ domains, an SH3 domain, and a guanylate kinase (GuK) domain.
PDZ-domain interactions are believed to play a role in receptor and channel clustering, contributing to neuronal plasticity. SAP102 is associated with NMDA receptors and shaker-type potassium channels at the synaptic membrane in CNS neurons.
Proteins sharing the T/SXV C-terminal motif (e.g., β1 adrenergic receptor, serotonin receptors, sodium and potassium channel subunits) may interact with SAP102 via PDZ domains.
Neuronal nitric oxide synthase (nNOS), although lacking the T/SXV motif, can associate with SAP102 through PDZ–PDZ interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.