Thermo Fisher Scientific Ataxin 7 Polyclonal Antibody
Ataxin 7 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 Affinity chromatography 정제, PBS/glycerol buffer 보존. 신경퇴행성 질환 연구용으로 적합.
- 카탈로그번호
- PA5118904
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Ataxin 7 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ATXN7 (Accession O15265), corresponding to amino acid residues P298–G348 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903404 |
Product Specific Information
Antibody detects endogenous levels of total ATXN7.
Target Information
Spinocerebellar ataxia type 7 (SCA7) is a hereditary neurodegenerative disease characterized by abnormally expanded polyglutamine (CAG) repeats at the N-terminus. This autosomal dominant cerebellar ataxia primarily affects the cerebellum, retina, and brain stem, leading to dementia, macular degeneration, and other neurodegenerative symptoms.
The SCA7 gene encodes the 892-residue protein ataxin-7, typically located in the cytoplasm and on the nuclear membrane of normal brain neurons. Mutations in the SCA7 gene cause ataxin-7 accumulation in intranuclear inclusions, resulting in cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-118904_Ataxin_7_O15265-1_Rabbit.svg, PA5-118904_Ataxin_7_O15265-1_Rabbit_PDP.jpeg)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.