Thermo Fisher Scientific SARS-CoV-2 3CLpro Recombinant Rabbit Monoclonal Antibody (8C4K3)
SARS-CoV-2 3CLpro 단백질을 표적하는 재조합 토끼 단일클론 항체로, WB, ICC/IF, ELISA에 적합합니다. 높은 특이성과 재현성을 제공하며, HEK293 세포에서 발현된 IgG 형 항체입니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8C4K3 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–306 of coronavirus SARS-CoV-2 3CLpro (YP_009725295.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3090469 |
Product Specific Information
Immunogen sequence:
MESLVPGFNE KTHVQLSLPV LQVRDVLVRG FGDSVEEVLS EARQHLKDGT CGLVEVEKGV LPQLEQPYVF IKRSDARTAP HGHVMVELVA ELEGIQYGRS GETLGVLVPH VGEIPVAYRK VLLRKNGNKG AGGHSYGADL KSFDLGDELG TDPYEDFQEN WNTKHSSGVT RELMRELNGG AYTRYVDNNF CGPDGYPLEC IKDLLARAGK ASCTLSEQLD FIDTKRGVYC CREHEHEIAW YTERSEKSYE LQTPFEIKLA KKFDTFNGEC PNFVFPLNSI IKTIQPRVEK KKLDGFMGRI RSVYPV
Target Information
Severe Acute Respiratory Syndrome (SARS), an emerging disease characterized by atypical pneumonia, has been attributed to a novel coronavirus (SARS-CoV).
The SARS 3C-like protease (SARS 3CLpro) is a cysteine protease responsible for proteolytic cleavage of the viral precursor polyprotein into functional proteins required for coronavirus replication.
It is considered an attractive target for therapeutic development against SARS.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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