Thermo Fisher Scientific PIK3CB Recombinant Rabbit Monoclonal Antibody (2F1B7)
PIK3CB 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot 및 ELISA에 최적화됨. 높은 특이성과 재현성을 제공하며, 연구용으로만 사용 가능.
- 카탈로그번호
- MA551436
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:8,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2F1B7 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 410–600 of human PI3 Kinase p110 beta (NP_006210.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.26 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094298 |
Product Specific Information
Immunogen sequence:
KVKTKKSTKT INPSKYQTIR KAGKVHYPVA WVNTMVFDFK GQLRTGDIIL HSWSSFPDEL EEMLNPMGTV QTNPYTENAT ALHVKFPENK KQPYYYPPFD KIIEKAAEIA SSDSANVSSR GGKKFLPVLK EILDRDPLSQ LCENEMDLIW TLRQDCREIF PQSLPKLLLS IKWNKLEDVA QLQALLQIWP K
Target Information
PIK3CB (phosphatyidylinositol 4,5-biphosphate 3-kinase catalytic subunit beta isoform) is a phosphoinositide-3-kinase that phosphorylates PtdIns (phosphatidylinositol), PtdIns4P (phosphatidylinositol 4-phosphate), and PtdIns(4,5)P2 (phosphatidylinositol 4,5-biphosphate) to generate phosphatidylinositol 3,4,5-triphosphate (PIP3).
PIP3 plays a key role in recruiting PH domain-containing proteins to the membrane and activating signaling cascades involved in cell growth, survival, proliferation, motility, and morphology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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