Thermo Fisher Scientific PHGDH Monoclonal Antibody (OTI4A1), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

PHGDH gene encodes an enzyme involved in the early steps of L-serine synthesis in animal cells.
L-serine is required for D-serine and other amino acid synthesis.
The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity.
Mutations in this gene have been associated with congenital microcephaly, psychomotor retardation, and other symptoms.
Multiple alternatively spliced transcript variants exist, though most full-length forms are not yet defined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.