Thermo Fisher Scientific PHGDH Monoclonal Antibody (OTI5C4), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The PHGDH gene encodes an enzyme involved in the early steps of L-serine synthesis in animal cells.
L-serine is essential for the synthesis of D-serine and other amino acids.
This enzyme requires NAD/NADH as a cofactor and forms homotetramers for its activity.
Mutations in this gene have been associated with congenital microcephaly, psychomotor retardation, and other neurological symptoms.
Multiple alternatively spliced transcript variants exist, though the full-length nature of most is not yet determined.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.