Thermo Fisher Scientific PRPK Polyclonal Antibody
PRPK 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Human 및 Rat 시료에 반응합니다. Western blot과 Immunocytochemistry에 적합하며, 고순도 Affinity Chromatography 정제 제품입니다. PBS/sucrose buffer에 보관되며 -20°C에서 안정적입니다.
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human TP53RK (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2605905 |
Product Specific Information
- Peptide sequence:
MAAARATTPA DGEEPAPEAE ALAAARERSS RFLSGLELVK QGAEARVFRG - Sequence homology: Human: 100%
Target Information
Component of the EKC/KEOPS complex required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is involved in transferring the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.
TP53RK exhibits ATPase activity within the EKC/KEOPS complex and likely supports the catalytic subunit OSGEP. It is an atypical protein kinase that phosphorylates Ser-15 of p53/TP53 protein and may participate in its activation.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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