Thermo Fisher Scientific PIGA Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PIGA. Recombinant protein control fragment (Product #RP-91907). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PIGA,uniProtId:P37287-1,ncbiNodeId:9606,antigenRange:159-270,antigenLength:484,antigenImageFileName:PA5-51527_PIGA_P37287-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51527_PIGA_P37287-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645541

Product Specific Information

Immunogen sequence: FADVSSVLTN KLLTVSLCDT NHIICVSYTS KENTVLRAAL NPEIVSVIPN AVDPTDFTPD PFRRHDSITI VVVSRLVYRK GIDLLSGIIP ELCQKYPDLN FIIGGEGPKR II

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

Target Information

This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.