Thermo Fisher Scientific PIGA Polyclonal Antibody
Human PIGA 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500–1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PIGA. Recombinant protein control fragment (Product # RP-91907) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645541 |
Product Specific Information
Immunogen sequence:
FADVSSVLTN KLLTVSLCDT NHIICVSYTS KENTVLRAAL NPEIVSVIPN AVDPTDFTPD PFRRHDSITI VVVSRLVYRK GIDLLSGIIP ELCQKYPDLN FIIGGEGPKR II
- Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 94%
Target Information
This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor.
The GPI anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface.
Paroxysmal nocturnal hemoglobinuria (PNH), an acquired hematologic disorder, results from mutations in this gene.
Alternate splice variants have been characterized.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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