Thermo Fisher Scientific HSD3B2 Polyclonal Antibody
HSD3B2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등에 사용 가능. 인간 및 생쥐 반응성, 항원 친화 크로마토그래피로 정제된 액상 항체. 4°C 단기, -20°C 장기 보관 권장.
- 카탈로그번호
- PA527775
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HSD3B2 Polyclonal Antibody
Thermo Fisher Scientific HSD3B2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 1–216 of Human HSD3B2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545251 |
Product Specific Information
- Recommended positive controls: HeLaS3, Molt-4
- Predicted reactivity: Dog (80%), Cat (81%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
3 beta-hydroxysteroid dehydrogenase (3β-HSD), also known as HSD3B1 or HSDB3, is a bifunctional enzyme essential in the synthesis of all classes of hormonal steroids. Two human 3β-HSD proteins, type I and type II, are expressed by different genes and function in distinct tissues.
Localized to the endoplasmic reticulum membrane and expressed in skin and placenta, the type I enzyme catalyzes the oxidative conversion of Δ5-ene-3β-hydroxy steroids and various ketosteroids.
Defects in the 3β-HSD gene are associated with salt wasting, genital ambiguity, hypogonadism, insulin-resistant PCOS, and increased prostate cancer susceptibility. Congenital deficiency of 3β-HSD activity can result in severe depletion of steroid formation, which may be lethal in young children.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.