Thermo Fisher Scientific PTGES2 Polyclonal Antibody
Goat polyclonal antibody targeting human PTGES2, validated for WB and IHC-P applications. Recognizes both PTGES2 isoforms. Supplied as liquid, unconjugated form with 0.5 mg/mL concentration. Suitable for prostaglandin E2 synthesis pathway research.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 5 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-RLKSRHRLQDNVRED (aa 292–306) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933923 |
Product Specific Information
- Expected to recognize both reported isoforms (NP_079348.1; NP_945176.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
The PTGES2 gene encodes prostaglandin E synthase 2 (PTGES2), an enzyme critical for the biosynthesis of prostaglandin E2 (PGE2) from arachidonic acid. It functions downstream of the cyclooxygenase (COX) pathway, interacting with COX-1 and COX-2. PTGES2 plays a key role in physiological and pathological processes such as inflammation, fever, and pain. As a membrane-associated protein, PTGES2 is distinct from other prostaglandin synthases due to its specific regulatory properties, contributing to precise PGE2 level control and signaling in immune and vascular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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