Thermo Fisher Scientific NALP5 Polyclonal Antibody
NALP5 단백질을 인식하는 Goat Polyclonal 항체로 인간 시료에 반응합니다. Western blot 및 Peptide ELISA에 사용 가능하며, 0.5 mg/mL 농도의 액상 형태입니다. 연구용으로만 사용되며, 신경 손상 관련 caspase 활성화 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DGSWHSFDEDDR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933920 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins, and are thought to be involved in inflammation and reproduction.
NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice.
Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons.
It may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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