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Thermo Fisher Scientific Factor VIII Polyclonal Antibody, FITC
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Thermo Fisher Scientific Factor VIII Polyclonal Antibody, FITC

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Human Coagulation Factor VIII를 인식하는 FITC 결합 토끼 폴리클로날 항체. Western blot, ELISA, IP에 사용 가능. 형광 특성(Excitation/Emission 498/517 nm). 액상 형태, 친화 크로마토그래피로 정제, -20°C 어둠 속 보관.

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FVIII-FITC
판매단위
pk
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마지막 업데이트 2025. 08. 05. 오후 09:47
Thermo Fisher Scientific FVIII-FITC Factor VIII Polyclonal Antibody, FITC 200 ul pk판매 단위 pk ·
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Thermo Fisher Scientific · Thermo Fisher Scientific Factor VIII Polyclonal Antibody, FITC

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1:500–1:1,000
ELISA 1:10,000
Immunoprecipitation (IP) 1:50–1:250

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide within amino acid region 200–250 of human Coagulation Factor VIII protein
Conjugate FITC (Fluorescein)
Excitation / Emission Max 498 / 517 nm
Form Liquid
Concentration 0.5–1.5 mg/mL
Purification Affinity chromatography
Storage Buffer Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA
Contains 0.02% sodium azide
Storage Conditions -20°C, store in dark
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation. Factor VIII acts as a cofactor for factor IXa, which, in the presence of Ca²⁺ and phospholipids, converts factor X to its activated form Xa.
Two alternatively spliced transcripts are produced:

  • Transcript variant 1 (isoform a): Encodes a large glycoprotein circulating in plasma, noncovalently associated with von Willebrand factor.
  • Transcript variant 2 (isoform b): Encodes a smaller protein primarily comprising the phospholipid-binding domain essential for coagulant activity.

Defects in this gene cause hemophilia A, a common recessive X-linked coagulation disorder.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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