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Thermo Fisher Scientific Factor VIII Polyclonal Antibody, FITC
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Human Coagulation Factor VIII를 인식하는 FITC 결합 토끼 폴리클로날 항체. Western blot, ELISA, IP에 사용 가능. 형광 특성(Excitation/Emission 498/517 nm). 액상 형태, 친화 크로마토그래피로 정제, -20°C 어둠 속 보관.
- 카탈로그번호
- FVIII-FITC
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오후 09:47
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Thermo Fisher Scientific FVIII-FITC Factor VIII Polyclonal Antibody, FITC 200 ul pk판매 단위 pk ·
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594,400원VAT 포함 653,840원
Thermo Fisher Scientific · Thermo Fisher Scientific Factor VIII Polyclonal Antibody, FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 200–250 of human Coagulation Factor VIII protein |
| Conjugate | FITC (Fluorescein) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation. Factor VIII acts as a cofactor for factor IXa, which, in the presence of Ca²⁺ and phospholipids, converts factor X to its activated form Xa.
Two alternatively spliced transcripts are produced:
- Transcript variant 1 (isoform a): Encodes a large glycoprotein circulating in plasma, noncovalently associated with von Willebrand factor.
- Transcript variant 2 (isoform b): Encodes a smaller protein primarily comprising the phospholipid-binding domain essential for coagulant activity.
Defects in this gene cause hemophilia A, a common recessive X-linked coagulation disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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