
Thermo Fisher Scientific Factor VIII Polyclonal Antibody
Thermo Fisher Scientific의 Factor VIII Polyclonal Antibody는 인간 응고인자 VIII을 인식하는 토끼 유래 IgG 항체로, WB, ELISA, IP에 적합합니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 고순도 친화 크로마토그래피로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50–1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 200–250 of human Coagulation Factor VIII protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Coagulation factor VIII participates in the intrinsic pathway of blood coagulation as a cofactor for factor IXa, which converts factor X to Xa in the presence of Ca²⁺ and phospholipids.
This gene produces two alternatively spliced transcripts:
- Transcript variant 1 encodes a large glycoprotein (isoform a) that circulates in plasma and associates with von Willebrand factor.
- Transcript variant 2 encodes a smaller protein (isoform b) containing the phospholipid-binding domain essential for coagulant activity.
Defects in this gene result in hemophilia A, a common recessive X-linked coagulation disorder.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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