Thermo Fisher Scientific Phospho-PKC zeta (Thr410) Monoclonal Antibody (S.447.6)
Phospho-PKC zeta (Thr410) 단일클론 항체로 인간, 마우스, 원숭이, 랫트 반응성. Western blot에 최적화된 rabbit IgG 형식. 세포 성장과 분화, 유전자 발현 등 PKC zeta 관련 연구에 적합. 액상 형태로 -20°C에서 보관.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| in situ PLA (PLA) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S.447.6 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pThr410 of human PKC zeta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10983263 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action, and substrate specificity.
PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca²⁺- and phospholipid-dependent. PKC zeta plays a key regulatory role in cellular functions including cell growth, differentiation, gene expression, hormone secretion, and membrane function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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