Thermo Fisher Scientific Phospho-PKC zeta (Thr410) Monoclonal Antibody (S.447.6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

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in situ PLA (PLA)

-

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Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

S.447.6

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pThr410 of human PKC zeta if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PKC zeta,uniProtId:Q05513-1,ncbiNodeId:9606,antigenRange:410,antigenLength:592,antigenImageFileName:MA5-15060_PKC_zeta_Q05513-1_Rabbit.svg,antigenImageFileNamePDP:MA5-15060_PKC_zeta_Q05513-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

<0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_10983263

Product Specific Information

It is not recommended to aliquot this antibody.

Target Information

The PKC family of serine/threonine kinases, including PRKCZ (PKC zeta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. PKC zeta plays a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.