Thermo Fisher Scientific Laminin gamma-1,2,3 Polyclonal Antibody
Laminin gamma-1,2,3 폴리클로날 항체로 인간, 마우스, 랫트에 반응합니다. WB, IHC, ICC 등 다양한 응용에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. ECM 연구용으로 적합하며, 동결건조 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 0.5–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.5–1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide mixture of laminin gamma1,2,3 (DLNKLNEIEGTLNKAKDEMK; MSELEERARQQRGHLHLLET; LQRKLSLLEQESQQQELQIQ) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746694 |
Product Specific Information
This antibody reacts with all three isoforms of Laminin gamma: Laminin gamma-1, gamma-2, and gamma-3.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Extracellular matrix (ECM) surrounds and separates most tissue compartments, determines tissue architecture, and dynamically interacts with its surrounding cells.
The basement membrane, part of the ECM, is composed of collagens, proteoglycans, elastin, and several glycoproteins, among which laminin is the most abundant.
Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains.
Dystroglycan is a major laminin receptor in muscle and epithelia, and nidogen is a high-affinity laminin-binding protein important for basement-membrane assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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